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A 46-year-old member asked:

can oral micronized progesterone [prometrium] make you gain weight?

2 doctor answers3 doctors weighed in
Dr. Valentin Drezaliu
Obstetrics and Gynecology 20 years experience
Yes: Progesterone increases your appetite as well as water retention, these 2 effects being associated with weight gain.
Dr. Cynthia Frazier
Gynecology 39 years experience
Rarely: Perimenopausal women rarely complain of weight gain when placed on natural progesterone. Most women feel better and sleep better on natural progesterone but there are exceptions.

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Last updated May 11, 2019
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