A member asked:

How long does prometrium (micronized progesterone) stay in your system? does it build up over time and how long before its depleted?

A doctor has provided 1 answer

About 1 day: Half life is around 28 hours, meaning half is gone every 28 hours you don't take it. You don't build up a store of it either. So within a few days, it is gone from your system hope that helps.

Answered 2/6/2021

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Please describe the medication: prometrium (micronized progesterone)?

2 doctors weighed in across 2 answers