Why do pediatric patients require lower doses of drugs than other patients?

Size: This depend on the type of drug and its basic metabolism along with the problem being treated. Most medication in kids as prescribed based on their body mass or weight, which is the container the drug must enter and distribute at a level that will do the job. Drugs are removed from the body by metabolism,in the urine or in the bile. Adults achieve a relatively uniform size.

Based on body weight: Pediatric patients are small and come in all sizes and weights The dose of most medicines and drugs is base on their body eight and calculate as mgm/kgm of body weight or ml/kgm of body weight

Pediatric doing : Most medications are calculated according to the body weight in KG, or by surface area, or according to age for example under 2 yrs, 2- 6 years, 6-12 years & 12 yrs & up. Therefore pediatric dose is usually less than adult dosage. I hope that answer your question