Many things: Mania can happen on its own, with no apparent cause aside from the underlying illness. Nonetheless, several possible triggers are known and include: sleep deprivation stress antidepressant medications anticholinergic medications drugs of abuse Speaking of abused drugs, stimulants like meth or cocaine are well known. However, marijuana can be a really potent mood destabilizer in bipolar disorder.
Answered 11/28/2017
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