A member asked:

Can prednisone make you feel angrier and almost psychotic? dose was 20mg for 5 days, on 2nd day of 10mg two days to go.

4 doctors weighed in across 2 answers
Dr. Mark Weston answered

Specializes in Orthopedic Spine Surgery

Yes: i warn my patients about feeling nervous and having extra energy and inability to be calmtemporary water retention is also a common complaint

Answered 5/1/2016

3.4k views

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Yes: Indeed it can have this side effect, and it is not uncommon. It should be getting better as you lower the dose, and it should go away.

Answered 5/1/2016

2.7k views

Thank

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