A member asked:

How long do u have to wait to start taking st. john wort after being on 10 mg prozac (fluoxetine)?

A doctor has provided 1 answer

Prozac (fluoxetine) has a: long half-life and doesn't work its way into the nervous system at the proper depth to begin to alter mood for about 14 to 21 days, in most cases. Some folks think a month is not too long to wait. (This is not the same as the initial "rush" some patients experience as the drug first is introduced...) Quitting Prozac (fluoxetine) takes about the same time to leave the body, so give it 2+weeks to be safe.

Answered 5/12/2016

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