A 34-year-old male asked:
How long will diflucan (fluconazole) stay in my body affecting Valium dosing? I'm extremely tired while taking both together.
1 doctor answer
Dr. Martin Raff answered
55 years experience in Infectious Disease
Fluconazole/diazepam: Fluconazole considerably increases exposure to diazepam. Recurrent administration of diazepam increases the risk of clinically significant interactions during fluconazole treatment, because the elimination of diazepam is impaired significantly. The plasma half-life of fluconazole is approximately 30 hours, and reducing the plasma levels will take 5-6 half-lives. This means 180 hrs or about 7+ days
Answered on Dec 9, 2014
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