A member asked:

How long will diflucan (fluconazole) stay in my body affecting valium dosing? i'm extremely tired while taking both together.

2 doctors weighed in across 2 answers

Fluconazole/diazepam: Fluconazole considerably increases exposure to diazepam. Recurrent administration of diazepam increases the risk of clinically significant interactions during fluconazole treatment, because the elimination of diazepam is impaired significantly. The plasma half-life of fluconazole is approximately 30 hours, and reducing the plasma levels will take 5-6 half-lives. This means 180 hrs or about 7+ days

Answered 12/9/2014

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3 days: The half life of diflucan (fluconazole) is 30 hours so after a couple of half lives the affect on other medicine should be fading.

Answered 12/22/2014

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Is it possible for body be immune to diflucan (fluconazole)?

A doctor has provided 1 answer