If have some acquired hypermobile joints w/o symptoms, can joints above or below loose joint become loose as well?

All of them: ? If have Hypermobility Syndrome can isolated joints be more or less loose than others. No, all body ligaments have similar degrees of genetically increased laxity; especially spine where all ligaments are physiologically similar. The entire musculoskeletal system is homogeniously rubbery; in keeping with each individual's unique Hypermobility trait penetrance.