Usually not much: These genetic variations (or polymorphisms) are very common. We're still learning about their effects on health. Compound heterozygous usually means you have 1 copy of the c677t variant and 1 copy of 1298c. If you enjoy good health you will probably have no problem. You might take the L-5-MTHF form of folate (folic acid) as a precaution. See http://tinyurl.com/k6xo6xe & http://tinyurl.com/kwcwqcx
Answered 6/9/2015
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