What will happen to arthirtis if cortisone doesn't help?

Many choices: This depends on your diagnosis. We have different medications beyond cortisone. We want to use these other medication so we can avoid long term corticosteroids like prednisone because of the long term side effects and risks of chronic cortisone. Your physician can have you see a rheumatologist and depending on the we can use Methotrexate or other DMARDS or use a biologic like TNF inh

Nothing: if the pain is not livable, then surgery.