A member asked:

What is the biochemistry behind abilify (aripiprazole)?

2 doctors weighed in across 2 answers
Dr. John Moranville answered

Specializes in Psychiatry

Dopamine : Abilify (aripiprazole) is a dopamine agonist/antagonist. Up to 10 mg it increases dopamine activity , 10-20 mg it modulates dopamine activity and at 30 mg persistently blocks dopamine receptors

Answered 12/17/2014

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Dr. Alan Ali answered

Specializes in Psychiatry

Abilify (aripiprazole): Abilify (aripiprazole) is partial Dopamine agonist (some increase in dopamine) plus serotonin antagonist, both of which cause some agitation & sweating. It can treat psychotic disorders such as schizophrenia, Bipolar depression, and as adjunct to antidepressants in Major depression.

Answered 4/2/2015

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