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A member asked:
What are the odds that two parents (both carriers of sickle cell) will have offspring with sickle cell?
A doctor has provided 1 answer
25 %: Normal hemoglobin AA Sickle hemoglobin SS Sickle carrier (AS) So if both parents are carriers, then each has a AS genotype. ( roughly half of their hemoglobin is sickle m but they have no symptoms) the gametes ( SPERM OR EGGES) CAN BE either S or A , 50% chance of having S or A these are the possible offsprings AA 25% (normal), AS, SA 50% (carriers) , SS sickle cell disease 25%
Answered 6/21/2015
3.5k views
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