A member asked:

Help please? what is the probalility that two parents both carriers of sickle cell with bear offsprings who will be sickler?

A doctor has provided 1 answer

25% each conception: This pairing has only 3 potential outcomes.There is a basic risk that 25% of all conceptions will become sickle cell affected.50% would become carriers and 25% would carry no sickle defect. However, you could still have 4 sicklers in a row.

Answered 4/11/2014

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