MI
A 27-year-old male asked:
Why do i feel more alert after .5mg xanax (alprazolam) but sleepy after taking nuvigil 250 mg?why do i have paradoxical reaction?
1 doctor answer • 3 doctors weighed in

A Verified Doctoranswered
Internal Medicine 38 years experience
Not unusual: ADHD people typically have paradoxical reaction to stimulants. Furthermore mild amts of sedatives (xanax (alprazolam) or alcohol) inhibit inhibitor parts of the brain and cause excitation.
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3.5k viewsReviewed >2 years ago
Last updated Nov 21, 2014
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