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A 27-year-old male asked:

Why do i feel more alert after .5mg xanax (alprazolam) but sleepy after taking nuvigil 250 mg?why do i have paradoxical reaction?

1 doctor answer3 doctors weighed in
Dr. Matt Wachsman
A Verified Doctoranswered
Internal Medicine 38 years experience
Not unusual: ADHD people typically have paradoxical reaction to stimulants. Furthermore mild amts of sedatives (xanax (alprazolam) or alcohol) inhibit inhibitor parts of the brain and cause excitation.
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Last updated Nov 21, 2014


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