12.5 y/o id twin girls with bone age 12. 1.9%(ile) for height & no puberty. parents don't have short stature. wtg 4 karyotype and gh test. what else ?

History of growth &: physical / mental development- pre-, peri- & post-natal till now, with intrauterine & postnatal growth charts of head circumference, height, weight & BMI. 3- generation family history. Chromosomal Microarray has replaced karyotyping as standard of practice. Bone age films. Free T4, ultrasensitive TSH, IGF-1 & more that a pediatric endocrinologist & a geneticist will need for their evaluations.