I have graves disease.dr put me on beta blocker but not helping.on carbimazole for 4 days now.still overheated & pulpitation.when should l get relief?

Be patient: Hi. You poor thing, and right as summer's coming on! The main thyroid hormone, l-thyroxine, has a blood half-life of 7 days, so if you totally stop making it one day, 7 days later, you'll still have half as much circulating in the blood as you had on the day you stopped making it. Carbimazole dose may need to be further adjusted also. You can increase the beta-blocker anytime. Hang in there!

Time and dose: It usually takes a bit longer for the carbimazole to work, but in another 4-5 days you should be noticing some improvement, unless the dose is too low. B blockers work faster; you may need a larger dose if you are not noticing a reduction in palpitations. If you are not seeing some improvement in another 2-3 days, suggest calling your doctor.