A member asked:

How accurate is the quad afp test for down syndrome?

2 doctors weighed in across 2 answers
Dr. Dennis Higginbotham answered

Specializes in American Board of Obstetrics and Gynecology

About 85 to 90%: The screening does no detect all cases of down's syndrome.

Answered 5/27/2012

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Dr. Jay Park answered

75-85% detection: Quadruple screening includes afp, unconjugated e3, beta-hcg, and inhibin-a. This screening test detects 75-85 % of fetuses with down syndrome, with false positive rate at 5%.

Answered 9/28/2016

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