Active hormone: Hi. Vitamin D per se has no direct effect in the body. Vitamin D is 25-hydroxylated in the liver. 25-hydroxyvitamin D is converted to the active hormone, calcitriol, in a tightly regulated step in the kidneys. Calcitriol is the active agent. It regulates gene expression in target tissues (gut, bone, muscle, etc). Calcitriol helps with calcium homeostasis, bone & muscle health, balance, etc.
Answered 4/3/2016
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