Get Virtual Care
For Businesses
About Us
A member asked:
Can i have celiac if the blood and gene tests were positive, but biopsy was negative?
A doctor has provided 1 answer
Yes, you can: Celiac disease often presents in the small bowel as "patchy" so biopsies of only one area may not be representative. Also, if you have celiac disease but eliminated gluten long enough for classic villous blunting changes in the small bowel to have resolved, then biopsies will look normal & the disease may be missed. Talk to your doctor about definitive diagnostic criteria for your piece-of-mind.
Answered 4/21/2017
5.8k views
Thank
Related Questions
A member asked:
I had a biopsy for localized Discoid Lupus. It came back positive. Blood work shows 1:80 ANA, negative for DS-DNA and negative for SM Antibody. Should I be concerned that I also have SLE?
2 doctors weighed in across 2 answers
A member asked:
Is it possible to have celiac disease if you have positive biopsy yet negative DQ2/DQ8? I have fasciculations and they stop when i don't eat gluten.
3 doctors weighed in across 2 answers
A member asked:
Is it possible for a toddlers blood test to be negative for celiac disease but upon endoscopy or colonoscopy be found to indeed have celiac disease?
10 doctors weighed in across 2 answers
A member asked:
I have symptoms of celiacs disease but don't have it due to just having a negative blood test, what could it be ?
4 doctors weighed in across 3 answers
People also searched for:
My endoscopy biopsy looked exactly like something caused by Celiac disease but my blood test came back negative, what else could it be?
Is it absolutely impossible to have celiac disease without positive blood tests and biopsy? Even with all symptoms and other autoimmune diseases?
I tested positive for celiac disease through a blood test but waiting to get my biopsy done, but liver & spleen are enlarged can it be cancer?
I had a biopsy of my small intestine come back with elevated lymphocytes and all the blood came back negative for celiac disease. What r other reasons?
Blood tests negative for celiac, hla gene positive, biopsy positive. Could there be another cause for mucosal flattening?
Didn't find what you're looking for?
90,000 U.S. doctors in 147 specialties are here to answer your questions or offer you advice, prescriptions, and more.
Ask your questionMore of what we treat
Content on HealthTap (including answers) should not be used for medical advice, diagnosis, or treatment, and interactions on HealthTap do not create a doctor-patient relationship. Never disregard or delay professional medical advice in person because of anything on HealthTap. Call your doctor or 911 if you think you may have a medical emergency.
HIPAASecure
SOC 2 Type 2Certified
JCAHOAccredited
Download HealthTap
Video visit and message your doctor
