Ulceration: most stomach cancers have been shown related to helicobacter pylori. It has shifted the lesion from prepyloric to cardioesphageal in nature. The organism causes ulceration which heals by bringing bone stem cells to repair damagte and then the bug toxins converts to stem cells to malignant stem cells progressing to adenocarcinoma. The lesions then bleed, ulcerate and can obstruct.
Answered 11/15/2014
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