Several: Idiopathic is the most common cause. Others in no particular order are congenital defects like deformed vertebrae, Marfan's syndrome and Ehlers-Danlos (both connective tissue disorders) Infection of the spine and rarely tumors. Careful evaluation by a pediatric orthopaedist can usually sort them out. Thanks for Trusting HealthTap!
Answered 11/6/2014
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Molecular Genetics: Mutant genes on the short arms of Chromosomes 17 & 19 & the long arms of Chr.8, 9 & 17 confer Susceptibility to Adolescent Idiopathic Scoliosis Types I -V, respectively. Of 5 mutations associated with scoliosis & SVT, only Charcot-Marie-Tooth Syndrome is likely. Dr. Arnold named likely connective tissue disorders. Your doctor can order a Chromosomal Microarray & evaluation by a geneticist.
Answered 11/5/2014
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Manufacturing defect: Manufacturing defect because of bad genetic message, inadequate supply of raw material at critical time of growth and ossification,injury, other diseases interfering with bone formation.......
Answered 11/5/2014
3.6k views
Not known: Most scoliosis is idiopathic occurring in adolescent females. There are no well-accepted causes for this particular type of scoliosis. Vast majority of patients are otherwise healthy and have no previous medical history..Most other causes of scoliosis usually occur at younger age including congenital, and neuromuscular etiologies.
Answered 11/5/2014
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Posture &muscles are: dominant factors. The vertebral muscles, from vertebra to vertebra, linking vertebra ~3 vertebra apart & linking vertebra ~6 vertebra apart, bilateral differential use & strength is the dominant issue controlling both shifting alignment & vertebral shape over time. However, imbalances are rarely recognized by each person, or others, until abnormalities have become quite advanced.
Answered 11/5/2014
3.6k views
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