Will singulair (montelukast) help prevent an asa allergy?

Can help symptoms: If you mean, does taking singulair (montelukast) help prevent symptoms from Aspirin sensitivity in people known to have this problem? Yes, it can. It doesn't always work, but sometimes it works beautifully for this. In one study in italy, 4 weeks of pre-medication with singulair (montelukast) blocked nasal symptoms nearly completely when Aspirin was taken. http://www.ncbi.nlm.nih.gov/pubmed/14982510.