Yes, most of them: Beta blockers are either water soluble or lipid soluble. The latter cross the blood-brain barrier and act on the CNS (central nervous system). Atenelol and Naldolol are 2 water soluble ones that do not readily cross into the brain. Alpha blockers generally do act on the CNS, and the 2 most common side effects are hypotension and dizziness.
Answered 4/11/2020
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