Do any beta blockers act on central nervous system? labetalol, propranalol? what about alpha-1 blockers?

Yes, most of them: Beta blockers are either water soluble or lipid soluble. The latter cross the blood-brain barrier and act on the CNS (central nervous system). Atenelol and Naldolol are 2 water soluble ones that do not readily cross into the brain. Alpha blockers generally do act on the CNS, and the 2 most common side effects are hypotension and dizziness.