50 year old lady with manic disease constantly speaks most times during the day and will be visiting for 5 wks. no prescription taken. how do i get thru?

Relationship?: A lot depends on who she is to you. That's a long visit, so - if you are really close, it may be possible to gently introduce the subject. If not - don't even try - just plan lots of time apart. If close, talk in terms of yourself and don't cheat w/ "I" statements that are really not. Say things like "It's hard for me to pay attention even though I do care". or "I need some quiet time now", etc.