Been tkng duolexotine 60mg for 4 mnths for depression. i felt good for a while but now i feel awful hopeless like before. shuld i choose to stop tkng?

Not cold turkey: I never heard of the medication - but most Rx's - especially antidepressants - should not be stopped cold. Tapering is very important to avoid bad withdrawal reactions. Talk to the provider for suggestions on tapering. You probably had a placebo or expectancy response at first. That's good - it means your optimism resulted in relief. A CBT therapist can revive that for you if you tell them.