Not the same: Pepcid is a H2 blocker, nexium (esomeprazole) is a proton-pump inhibitor. Either should work for GERD. You should call the 800 number on your pharmacy card to ask about coverage. Since they are both now OTC it is less likely they will be covered. Nexium (esomeprazole) comes as "granules" that can be dissolved in fluid.
Answered 1/21/2018
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