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A member asked:
What's the difference between low ionized calcium and low calcium? which one is the true measure of hypocalcemia?
A doctor has provided 1 answer
Both: If you can measure (rarely done), calculate (complicated formula) or estimate (calcium minus albumin), you will get the ionized calcium. About half of the calcium in the blood is ionized and this is the active form. In real-life, this means that a lot of sick people with low albumin also have low total calcium but needn't worry as the physiologic ionized calcium is what's regulated.
Answered 9/28/2014
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