A member asked:

What are some reasons a positive ana can become negative and then positive again.

A doctor has provided 1 answer
Dr. John Chiu answered

Par for the course: The immune system is not a stagnant one and in fact likely the most active system in the body. Thus the level of activities vary constantly. However, it would be unlikely for a high ANA titer (1:128) or above to become negative altogether at any time without medication.

Answered 4/1/2019

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