Local approach: Precancerous cells from a Pap represent transforming cells of the cervical and endocervical canal. By definition they have not yet invaded the muscular layers of the cervix but are contained within the basement membrane that cordons off the smooth muscle layers of the cervix from the lining layers. At this time cryosurgery can be employed or a more aggressive cone cut from the cervical os.
Answered 10/21/2015
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