United Kingdom

A 35-year-old male asked:

Is amitriptyline good for idiopathic nerve pain in legs ?

1 doctor answer • 2 doctors weighed in

Dr. Mark Fisheranswered

Neurology 31 years experience

Yes, but...: Zoloft (sertraline), (sertraline) tramadol and amitriptyline all increase serotonin levels. Amitriptyline also potentiates this effect of Zoloft (sertraline). BTW, Zoloft (sertraline) decreases the effect of tramadol by affecting hepatic metabolism. Gabapentin has no drug interactions at all. Adding amitriptyline at LOW doses may help, with CLOSE monitoring. Read up on serotonin syndrome. It's rare and usu. not life-threatening but be aware of it.

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Dr. Evan Altman

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I have excessive weakness in my legs if i sit for a long period I have to have help getting up and i even have the same problem with my arms and hands. My doctor has treated me with elavil (amitriptyline) and effox and no help

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I have been getting Pains up and down my legs starting from the feet/ankles then also into my arms which make my hands do a wierd twitch spasm. My doctor has prescribed amitriptyline but I thought this was an anti depressant?

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Can amitriptyline actually cause burning pain in feet and legs. Taking it to reduce that symptom ?

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Last updated May 22, 2016

Found in:

Nerve›Pain›Neuralgia

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