A member asked:

What is fish scale disease, and why does it affect skin pigmentation?

3 doctors weighed in across 2 answers
Dr. Karen Han answered

Ichthyosis: Ichthyosis (fish scale disease) is an inherited condition characterized by dry scaly skin as a result in defective skin barrier function. The most common subtype is ichthyosis vulgaris, which is pigmentless.The rare subtype, epidermolytic hyperkeratosis, is characterized by retained thickened scales in skin folds, giving the appearance of "dirty skin" even though no pigment is actually deposited.

Answered 12/28/2014

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Icthyosis vulgaris: A disorder characterized by the development of dry, rectangular scales. This is a disorder of keritinization, which affects the color and texture of the skin.

Answered 1/5/2019

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