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A 21-year-old member asked:

What exactly causes a skin pigmentation disorder?

2 doctor answers3 doctors weighed in
Dr. Chakshu Gupta
Pathology 24 years experience
Various: Skin pigmentation can be affected by heriditary disorders, drugs, infections, inflammation, sun exposure, skin cancers, immune diseases or even tumors of internal organs. You are probably referring to vitiligo, which is essentially a auto-immune condition or to albinism, which is genetic.
Created for people with ongoing healthcare needs but benefits everyone.
Dr. Robert Jackson
Dermatology 44 years experience
It depends: Most of the time the immune system is involved the skin is inflammed and the skin lightens or darkens depending on the disorder.
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Similar questions

A 22-year-old member asked:

Can lupus cause a skin pigmentation disorder?

2 doctor answers2 doctors weighed in
Dr. Karen Han
Dermatology 24 years experience
Sometimes...: We generally talk about lupus in 2 categories: systemic and cutaneous (localized in skin). A subtype of cutaneous lupus called discoid lupus can cause dyspigmentation and scars in the areas of involvement. Unfortunately, when chronic, the dyspigmentation becomes more or less permanent. Systemic lupus can be associated with other autoimmune disorders such as vitiligo (depigmentation disorder).
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Last updated Mar 16, 2020
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