It can happen: One of the known side effects of zonisamide (Zonegran®) is "pain, burning, numbness, or tingling in the hands or feet." The important thing is that you've notified your neurologist and a medication change was made hat has relieved the burning. Further reading: http://www.nlm.nih.gov/medlineplus/druginfo/meds/a603008.html
Answered 9/29/2016
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