A member asked:

Doctors, what are your experiences with methotrexate / how does it feel like?

A doctor has provided 1 answer
Dr. Thomas Namey answered

Specializes in Rheumatology

Very good drug.: Mtx tabs are 2.5mg. Taken orally, they are in the gut @600x that will be in the blood strea. Absorption is variable-40-90%. Then to the liver which sees 400x that which will be diluted out. None of these are significant issues when given by a weekly subcutaneous injection. Mtx is a valuable drug for inflammatory arthritis, psoriasis, and many autoimmune diseases. I only gibe it subcu!

Answered 11/26/2013

5.8k views

Thank

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