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A 45-year-old member asked:

Anyone have mastocytosis? what is it?

2 doctor answers3 doctors weighed in
Dr. Regina Hampton
Breast Surgery 23 years experience
Skin problem: This is a skin disorder. I recommend asking a dermatologist this question.
Dr. Brant Ward
Allergy and Immunology 13 years experience
Too many mast cells: Mastocytosis is an overgrowth of mast cells, immune cells that release histamine and other chemicals upon activation. There are several forms, from small collections of cells in the skin (urticaria pigmentosa) to increased numbers in the bone marrow and throughout the body (systemic mastocytosis). Symptoms vary from hive-like reactions to recurrent anaphylaxis. See a specialist for more details.

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A 38-year-old member asked:

Anyone here have treated mastocytosis?

1 doctor answer1 doctor weighed in
Dr. Brant Ward
Allergy and Immunology 13 years experience
Many doctors do: Mastocytosis of the skin is relatively common (esp. In childhood), and most dermatologists will be familiar with it. More extensive/complex skin disease, mast cell activation disoreders, or systemic mastocytosis (throughout the body, not just skin) should be seen by an expert. The mastocytosis society maintains a list of experts by region on their website (www.Tmsforacure.Org).
A 37-year-old member asked:

What is mastocytosis?

1 doctor answer5 doctors weighed in
Dr. Brant Ward
Allergy and Immunology 13 years experience
Too many mast cells: Mastocytosis is an overgrowth of mast cells, immune cells that release histamine and other chemicals upon activation. There are several forms, from small collections of cells in the skin (urticaria pigmentosa) to increased numbers in the bone marrow and throughout the body (systemic mastocytosis). Symptoms vary from hive-like reactions to recurrent anaphylaxis. See a specialist for more details.
A 47-year-old member asked:

Anyone diagnosed mastocytosis? How?

2 doctor answers4 doctors weighed in
Dr. Regina Hampton
Breast Surgery 23 years experience
Skin problem: This is a skin disorder. I recommend asking a dermatologist this question.
A 32-year-old member asked:

Anyone have a baby with mastocytosis?

1 doctor answer2 doctors weighed in
Dr. David Rosenfeld
Pain Management 27 years experience
Yes: There are no accurate data on the frequency of mastocytosis. Annual incidence of 5-10 new cases per million population is estimated. In dermatological practices and hospital departments of dermatology, 1 of every 1000 to 8000 new patients has mastocytosis. The most frequently encountered forms are cutaneous mastocytosis and indolent systemic mastocytosis. The least common is mast cell leukemia.

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Last updated Jan 5, 2019

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