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A 40-year-old member asked:

How to control mastocytosis?

2 doctor answers2 doctors weighed in
Dr. Brant Ward
Allergy and Immunology 13 years experience
Certain meds: Cutaneous masto can be treated with daily oral antihistamines or cromolyn applied to the skin, but sometimes may not need treatment. Systemic masto is usually treated with antihistamines, plus oral cromolyn for GI symptoms and epipen (epinephrine) for anaphylactic episodes. Aggressive forms may only respond to certain chemotherapy agents. See a specialist in masto for more information.
Dr. Brant Ward
Allergy and Immunology 13 years experience
Medications can help: Cutaneous (skin-only) mastocytosis can be treated with antihistamines, singulair, (montelukast) and topical cromolyn if the itching, etc., is problematic. The same meds can help systemic mastocytosis, with swallowed cromolyn for GI symptoms. Epinephrine can help resolve anaphylaxis if that occurs. Avoid codeine/opiates and other meds that directly activate mast cells. Talk with a specialist for more info.

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A 37-year-old member asked:

What is mastocytosis?

1 doctor answer5 doctors weighed in
Dr. Brant Ward
Allergy and Immunology 13 years experience
Too many mast cells: Mastocytosis is an overgrowth of mast cells, immune cells that release histamine and other chemicals upon activation. There are several forms, from small collections of cells in the skin (urticaria pigmentosa) to increased numbers in the bone marrow and throughout the body (systemic mastocytosis). Symptoms vary from hive-like reactions to recurrent anaphylaxis. See a specialist for more details.

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Last updated Jul 9, 2015

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