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A member asked:
Does the western blot trump the elisa? tested positive via elisa igg for hsv2,but later tested negative via western blot. no symptoms. do i have hsv2?
A doctor has provided 1 answer
Western blot more: specific, ELISA more sensitive. One positive ELISA and one negative Western blot says that you do not have enough antibodies to HSV 2 for confirmation of diagnosis. It may be prudent to repeat the tests in 3-4 months to make sure that negative Western blot was not due to incomplete/early immune response.
Answered 5/20/2016
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