A member asked:

Hematocrit normal but got high mcv.could having pernicious anemia be the cause of my long term panic disorder?b12 produces neurotrans.through methylat

2 doctors weighed in across 2 answers

Possibly: Low B12 leading to pernicious anemia will cause MCV to rise as can folic acid and thryoid disease. Alcohol related blood dyscrasia can elevate MVC, as can other types of liver disease. If you hemaglobin/hematocrit is normal that pretty much rules out pernicious anemia unless very early stages. http://emedicine.medscape.com/article/203858-overview#a0104 Recommend some additional testing.

Answered 8/23/2014

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Dr. Matt Wachsman answered

Specializes in Internal Medicine

Could be: but isn't. a b12 level will confirm that the amount in your system is more than adequate. b12 is in all animal products and is stored for months. Deficiencies occur: in the elderly with very thin absorption areas in the gut that can't get it in. rare parasitic diseases total hardcore Vegans

Answered 8/23/2014

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