A member asked:

Folic acid -24.6, serum b12 - 600, high folic acid may mask b12 def, what does that mean? is serum b12 falsly high? what other tests for b12 def?

5 doctors weighed in across 2 answers

See below: Folic acid does not affect blood test results for B12, i.e., it will not cause falsely high B12 results. High folic acid may mask hematologic effects of B12 but not all functions of B12.

Answered 8/22/2014

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Dr. Randy Baker answered

Specializes in Holistic Medicine

Not to worry: Folic acid can mask the SYMPTOMS of B12 deficiency but will not mask or alter test results for B12. A more sensitive test for B12 deficiency is methylmalonic acid but I don't think you need it. See http://chriskresser.com/b12-deficiency-a-silent-epidemic-with-serious-consequences & http://www.aafp.org/afp/2003/0301/p979.html

Answered 8/24/2014

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