Thyroxine dosage: If you are hypothyroid and your TSH is elevated, you do need thyroxine. The dosage needed should be adjusted, measuring your blood level of free T4 and T3, (liothyronine) and giving only as much as is needed to lower your TSH to the normal level. This is independent of your pernicious anemia. You don't have thyroxine intolerance, but you may need a relatively smaller dose (the amount needed varies for each).
Answered 8/19/2014
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