For a small staff infection is mupirocin ointment enough by its self?

Probably ok: Probably, you should try it for 1 or 2 days, if there is no improvement in symptoms, then you will likely need oral antibiotics, and will need to see your doctor

Here are some ...: External antibiotic use would have no effect or help an enclosed skin infection like a boil; its treatment of choice would be incision and drainage with optional internal use of antibiotic according to clinical judgment. More? Ask Doc. .