A member asked:

Is macular degeneration genetic?

5 doctors weighed in across 4 answers

Yes: The lifetime risk of developing late-stage macular degeneration is 50% for people that have a relative with macular degeneration, versus 12% for people that do not have relatives with macular degeneration, a fourfold higher risk.

Answered 8/7/2013

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Some: There are a few inherited forms especially those in the young and those associated with drusen deposits that have strong inheritance. Less certain is the inheritance pattern of ordinary, older age macular degeneration - the data is still being worked out. You can help protect your macula with a good diet, avoidance of sunlight and stopping smoking.

Answered 5/18/2014

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Yes: Certain genetic variations (such as in the complement factor system) that are inherited put you at increased risk for macular degeneration.

Answered 11/6/2012

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Yes: There is a strong genetic association with macular degeneration invoking multiple genes

Answered 9/19/2015

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