A member asked:

Went from 300 mg wellbutrin (bupropion) sr to 400mg wellbutrin (bupropion) sr. take 200mg in morning and 200mg at noon. is that normal dosing. been a little sick.

3 doctors weighed in across 2 answers

Yes wellbutrin (bupropion) dose: Wellbutrin (bupropion) comes in 3 forms: immediate release (IR), 12hour release (SR) and 24 hour (XL). There is a small risk of seizure if blood levels rise too high so guidelines suggest that IR doses shouldn't exceed 150mg spaced 6-8 hours apart; SR can be up to 200mg spaced 6-8 hours apart; XL can take 450mg once daily. Total daily doses above 450mg are generally not recommended.

Answered 5/8/2016

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Dr. Alan Ali answered

Specializes in Psychiatry

Wellbutrin (bupropion) dose: Usual daily dose is 300-450mg. as tolerated. Let your doctor know of your symptoms.

Answered 4/30/2015

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