A member asked:

Which benzo is harsher on your liver--klonopin or ativan (lorazepam)?

4 doctors weighed in across 2 answers

Clonazepam: Benzodiazepines are rarely associated with elevated liver functions or clinically apparent liver injury and have not caused acute or chronic liver failure. However, there have been a few case reports about Clonazepam irritating the liver [none about Ativan] and therefore it would be considered slightly harsher.Their effect on the liver is probably due to a rarely produced intermediate metabolite.

Answered 10/24/2017

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Dr. Krishna Kumar answered

Specializes in Psychiatry

Benzodiazepine Depen: Let the Wise Person in you ask: •Reasons for taking Ativan or Klonopin ••Reasons for concern fort effect on liver not a common side effect. •Tolerance •Habit forming •Withdrawal •Use of Alcohol •Stresses in life causing Anxiety See Psychiatrist for: Duration, Dose and Frequency •Tolerance and Habit forming of Ativan and Klonopin •Therapy for stresses of life and medication dependency •Relaxation

Answered 3/22/2020

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