Is acid reflux worse on an almost empty stomach?

It can be: yes it can because you have acid in your stomach all the time actually food will dilute some of the acid but food will stimulate the stomach to produce more acid the bottom line is yes it can happen you can use anti acid make sure you stay on medicine all the time not only when you are having heartburn or diluted with red vinegar if not better you better see a doctor for endoscopy to make sure yo