I am taken 5 mg oxycodone 5 times a day and i chew tobacco. should i try getting off both of them at once or one at time?

Neurotransmitters: You are doing those things mainly to correct a neurotransmitter imbalance that you were possibly born with. You can get off both together, but best do it under the care of a physician who is skilled at balancing neurotransmitters.

Visit your doctor: Not dangerous to stop either. Oxycodone at that dose will not produce a devastating withdrawal syndrome, but it could still be mildly unpleasant: sweats, diarrhea, body aches. Avoidable by tapering off under the care of a MD. Tobacco - toss it. Good luck!!