A member asked:

Can you tell me about immunity and i am having a difficult time with finding information on hypergammaglobulinemia. so my question is what is it?

4 doctors weighed in across 2 answers
Dr. Michael Rupp answered

Specializes in Allergy and Immunology

Low IgG: Immunoglobulins are a type of protein made by your body to help protect it against infections. There are five types of immunoglobulins: IgA, IgD, IgE, IgG, and IgM. Each of these has a slightly different function in infection fitting. Hypogammaglobulinemia refers to low levels of IgG the primary infection fighting antibody. The most common form in adults is common variable immune deficiency.

Answered 2/11/2015

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Dr. John Chiu answered

Hypergammaglobulinem: This may reflect a chronic infection or overproduction of gammaglobulin which may have no immune function and may be harmful. You need to consult an allergist/immunologist if the level is consistently higher than the upper limit (perhaps by 20%).

Answered 2/17/2016

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