A member asked:

Can you tell me in parkinson's disease, is glutamate over or under produced?

A doctor has provided 1 answer
Dr. Mark Fisher answered

Specializes in Neurology

You asked for it: Excessive glutamatergic signaling within the basal ganglia is implicated in the progression of Parkinson’s disease. Does that answer your question? -- If you really want to get deeper into the pain, there is a recent review: "Metabotropic Glutamate Receptors for Parkinson's Disease Therapy" at http://www.hindawi.com/journals/pd/2013/196028. Don't say I didn't warn you.

Answered 9/28/2016

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