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A member asked:

Which genetic test is performed in diagnostic workup of systemic mastocytosis? apart from trypsine and ige, which allergo-tests would you recommend?

A doctor has provided 1 answer

Codon 816: A mutation of A to T at codon 816 of c-kit can be tested for but is not widely available. Other tests are 24 hour urine for histamine metabolites, abnormal mast cell membrane Immunophenotype, and of course studies of mast cells in bone marrow, alpha form of tryptase levels.

Dr Iwata agreed

Answered 7/21/2014

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My mother is having cough from 3 years It settles down a bit and again becomes more. We have consulted doctors but nothing helped. All tests are normal. Ige level seems to be increased. But no medicine helps. We can't find what she is allergic of?

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