2 years ago, i had knee replacement. after extensive p/t, i am suffering with spasms in the knee area at night or when relaxing. my doc prescr. flexeril (cyclobenzaprine hcl) 5 mg. at night. no relief. help.

Second opinion?: It might be time to get a second opinion. You could certainly also go back to your current treating doctor and let them know that you have had no relief.

Could be nerves : During any limb surgery, especially of this type, nerves can be damaged on the process. As those nerves regenerate, and heal they may induce fasciculations and spasms of the muscles around the surgical site. A visit to a neurologist may help elucidate the issues as they can actually test the nerves involved and give a more precise answer and prognosis.